22nd May 2024 - Categories: Research & Development
A detailed characterization of the REH cell line using combination of short- and long-read DNA and RNA sequencing.
10th October 2023 - Categories: Research & Development
Open-source genomic, transcriptomic and epigenomic data sets (raw sequencing reads as well as assemblies and mapped BAM files) for a leukemic cell line (REH), available to the research community.
24th August 2023 - Categories: Research & Development
Showing the promise of long-read sequencing toward characterization of the full spectrum of genetic variation in single cells.
6th April 2022 - Categories: Research & Development
Introducing single cell Splinted Ligation Adapter Tagging (scSPLAT), a scalable plate-based protocol for single-cell WGBS library preparation, offering sample preparation at a higher scale and throughput.
4th September 2020 - Categories: Research & Development
Sarek: an open-source bioinformatic tool to detect germline variants and somatic mutations based on sequencing data from WGS, whole-exome sequencing (WES), or gene panels. Sarek offers easy, efficient, and reproducible analyses, and can readily be used both as a production workflow at sequencing facilities and as a powerful stand-alone tool for individual research groups.
13th February 2020 - Categories: Research & Development
Presenting a framework for high-quality bioinformatics pipelines that can be used across all institutions and research facilities.
23rd August 2017 - Categories: Research & Development
SweGen: generating a comprehensive data resource for population-based genetic variants that describes the landscape of genetic variation in the Swedish population
2nd May 2017 - Categories: Research & Development
Cluster Flow: a simple and flexible bioinformatics pipeline tool designed for quick and user-friendly installation, offers next-generation sequencing data analysis with pre-configured modules and pipelines for common bioinformatics tasks.
7th April 2017 - Categories: Research & Development
Presenting a novel approach for quick and cost effective WGBS library preparation that is based on splinted adaptor tagging (SPLAT) of bisulphite-converted single-stranded DNA.
19th October 2016 - Categories: Research & Development
MultiQC: a bioinformatics tool that automates the parsing of NGS metadata, creating a single summary report with powerful visualizations and a simple interface. MultiQC enables researchers to quickly identify global trends and biases, improving quality control processes and reducing the risk of batch effects in large-scale sequencing studies.