Date: June 11, 10.30-11.30 in Trippelrummet, Navet, SciLifeLab Uppsala and online Title: Genome sequencing of 15,000 healthy elderly Australians: implications for clinical genetics Speaker: Dr. Paul Lacaze, Head of the Public Health Genomics Program, Monash University, Melbourne Australia

The ASPREE Healthy Ageing Biobank contains ~15,000 consented samples from individuals aged 70 years or older participating in the ASPirin in Reducing Events in the Elderly (ASPREE) study – Australia’s largest clinical trial and longitudinal study of healthy ageing. All ASPREE biobank samples are being sequenced using a targeted ‘super-panel’ of 750 genes used commonly in clinical testing, Over 11,500 samples have been sequenced (May 2018), identifying hundreds of actionable pathogenic variants in individuals lacking any apparent signs and symptoms of genetic disease beyond 70 years. Results will be presented on these findings, with implications for our understanding of penetrance and clinical actionability for genes used in routine testing. BiG Talks – Bioinformatics and Genomics seminar series arranged in collaboration with SciLifeLab platforms NBIS, NGI and CG

For more information and to register, please visit the SciLifeLab website.

Order processing and sample submission for sequencing will be closed during summer. Library preparation and sequencing will continue at a reduced pace.

• Order submission at the NGI Order portal will be closed from June 18 to August 6. Only complete orders will be processed at June 18.
• Sample submission will be closed from June 29 to August 6.

Are you a visionary researcher within genomics with experience of operating or supervising infrastructures? Are you ready to take a major leadership roles in genomics? SciLifeLab now seeks a Director and a Co-Director to head the national Genomics Platform and high-throughput sequencing. An expressions of interest to these positions from both national and international candidates are welcomed!

Read more at SciLifeLab website.

Är du en utbildad biotekniker, molekylärbiolog eller liknande med hög noggrannhet, ansvarskänsla och god samarbetsförmåga? Har du praktisk erfarenhet av storskaligt laboratoriearbete, gärna i ackrediterad miljö och med datorstyrda laboratorieinstrument? NGI Uppsala söker nu en forskningsingenjör till sekvenseringsenheten av SNP&SEQ-teknologiplattformen. Arbetet omfattar DNA-sekvensering med modern instrumentering från Illumina såsom HiSeqX, NovaSeq, HiSeq2500 och MiSeq.

Läs mer om tjänsten och ansök på UU hemsida.

Do you want to work in one of the world’s fastest growing technology areas? NGI Uppsala (the SNP&SEQ Technology Platform)are currently looking for two bioinformaticians responsible for managing and analyzing the sequence data produced by the platform, as well as the development and maintenance of pipelines for data analysis.

Read more and apply at UU website.

Would you like to work in a dynamic environment in one of Europe's largest sequencing centres? Are you service minded molecular biologist with good communication and organizational skills who would like to work in an area of rapid technology and application development? NGI Stockholm is right now looking for a Junior Project Administrator and a Project Coordinator.

Read more and apply at the KTH website