Spatial transcriptomics (Visium)

Spatial transcriptomics allows you to map gene expression across intact tissue sections, combining histological context with transcriptome-wide profiling using 10x Genomics Visium platforms for fresh frozen and FFPE samples

Spatial transcriptomics enables the study of gene expression in intact tissue sections while preserving spatial information. This technology combines histological context with transcriptome-wide profiling, allowing researchers to map cell types, states, and interactions directly onto tissue architecture.

At NGI we provide support for several spatial transcriptomics approaches, primarily based on the 10x Genomics Visium platforms. These methods allow you to capture polyadenylated RNAs from fresh frozen tissues and use probes covering the whole transcriptome on FFPE tissues to generate high-resolution maps of gene activity. Our service includes guidance on sample preparation, library construction, sequencing, and basic downstream analysis.

Explore our current spatial transcriptomics applications below to find the approach that best suits your project. Please feel free to contact us contact us for advice on experimental design, tissue requirements, or other questions.