Production of high-quality proximity ligation libraries, using two restriction enzymes.
TADs illumina de novo chromatin scaffolding library preparation epigeneticsA proximity-ligation protocol using a sequence-independent endonuclease, generating data for TAD identification and scaffolding.
epigenetics TADs illumina de novo chromatin scaffolding library preparationNGI can generate high quality assemblies using IPA and hifiasm assemblers
hifiasm ipa hic omnic scaffolding assembly pacbio hifi