NEBNext EM-Seq kit is an alternative to whole-genome bisulfite sequencing (WGBS). The enzymatic conversion of unmethylated cytosines in EM-seq is more gentle to DNA than WGBS and results in libraries with more even genome coverage and better coverage of CpG sites across the genome.
illumina CpG WGBS EM-seq library preparation methylation epigeneticsA method to identify open chromatin regions, such as promotor areas, using a transposase.
ATAC-seq Omni-ATAC TN5 ATAC open chromatin epigenetics illumina ATACseqProfiling of chromatin accessibility at the single cell level.
single cell illumina ATAC-seq dna chromium chromatin 10x Genomics ATAC library preparation epigeneticsA proximity-ligation protocol using a sequence-independent endonuclease, generating data for TAD identification and scaffolding.
epigenetics TADs illumina de novo chromatin scaffolding library preparationSPLAT is an in-house developed WGBS library preparation method. This approach enables quick and efficient preparation of WGBS libraries from low-input DNA
single-stranded DNA ssDNA library preparation methylation epigenetics illumina CpG WGBS BisulphiteAnalysis of multiple validated epigenetic marks simultaneously in a single workflow.
modification library preparation methylation epigenetics illumina dna histone ChIPThe EPIC BeadChip array allows for the interrogation over 935,000 methylation sites quantitatively across the genome at single-nucleotide resolution.
dna array infinium CpG methylation epigenetics illuminaOxford Nanopore sequencers perform single-molecule long read sequencing of DNA and RNA
long reads ont direct RNA epigenetics nanopore