NEBNext EM-Seq kit is an alternative to whole-genome bisulfite sequencing (WGBS). The enzymatic conversion of unmethylated cytosines in EM-seq is more gentle to DNA than WGBS and results in libraries with more even genome coverage and better coverage of CpG sites across the genome.
WGBS EM-seq library preparation methylation epigenetics illumina CpGProduction of high-quality proximity ligation libraries, using two restriction enzymes.
TADs illumina de novo chromatin scaffolding library preparation epigeneticsA method to identify open chromatin regions, such as promotor areas, using a transposase.
ATAC-seq Omni-ATAC TN5 ATAC open chromatin epigenetics illumina ATACseqProfiling of cellular chromatin from individual cell nuclei.
single cell illumina ATAC-seq chromium 10x Genomics ATAC open chromatin library preparation epigeneticsA proximity-ligation protocol using a sequence-independent endonuclease, generating data for TAD identification and scaffolding.
epigenetics TADs illumina de novo chromatin scaffolding library preparationSPLAT is an in-house developed WGBS library preparation method. This approach enables quick and efficient preparation of WGBS libraries from low-input DNA
CpG WGBS Bisulphite single-stranded DNA ssDNA library preparation methylation epigenetics illuminamiRNA libraries from very low input total RNA samples & degraded total RNA.
library preparation epigenetics RNA illuminaThe EPIC BeadChip array allows for the interrogation over 935,000 methylation sites quantitatively across the genome at single-nucleotide resolution.
array infinium CpG methylation epigenetics illumina dna