NEBNext EM-Seq kit is an alternative to whole-genome bisulfite sequencing (WGBS). The enzymatic conversion of unmethylated cytosines in EM-seq is more gentle to DNA than WGBS and results in libraries with more even genome coverage and better coverage of CpG sites across the genome.
EM-seq library preparation methylation epigenetics illumina CpG WGBSProduction of high-quality proximity ligation libraries, using two restriction enzymes.
epigenetics TADs illumina de novo chromatin scaffolding library preparationA method to identify open chromatin regions, such as promotor areas, using a transposase.
ATACseq ATAC-seq ATAC open chromatin epigenetics illuminaProfiling of cellular chromatin from individual cell nuclei.
single cell illumina ATAC-seq chromium 10x Genomics ATAC open chromatin library preparation epigeneticsA proximity-ligation protocol using a sequence-independent endonuclease, generating data for TAD identification and scaffolding.
epigenetics TADs illumina de novo chromatin scaffolding library preparationSPLAT is an in-house developed WGBS library preparation method. This approach enables quick and efficient preparation of WGBS libraries from low-input DNA
CpG WGBS Bisulphite single-stranded DNA ssDNA library preparation methylation epigenetics illuminaGeneration of sequencing libraries from dicer cleaved miRNA.
epigenetics RNA truseq illumina library preparationGeneration of miRNA libraries from very low input total RNA samples and degraded total RNA.
library preparation epigenetics RNA illuminaThe EPIC BeadChip array allows for the interrogation over 850,000 methylation sites quantitatively across the genome at single-nucleotide resolution.
CpG methylation epigenetics illumina dna array infinium