NEBNext EM-Seq kit is an alternative to whole-genome bisulfite sequencing (WGBS). The enzymatic conversion of unmethylated cytosines in EM-seq is more gentle to DNA than WGBS and results in libraries with more even genome coverage and better coverage of CpG sites across the genome.
library preparation methylation epigenetics illumina CpG WGBS EM-seqProduction of high-quality proximity ligation libraries, using two restriction enzymes.
chromatin scaffolding library preparation epigenetics TADs illumina de novoA method to identify open chromatin regions, such as promotor areas, using a transposase.
ATAC open chromatin epigenetics illumina ATACseq ATAC-seq Omni-ATAC TN5Profiling of chromatin accessibility at the single cell level.
chromium chromatin 10x Genomics ATAC library preparation epigenetics single cell illumina ATAC-seq dnaA proximity-ligation protocol using a sequence-independent endonuclease, generating data for TAD identification and scaffolding.
de novo chromatin scaffolding library preparation epigenetics TADs illuminaSPLAT is an in-house developed WGBS library preparation method. This approach enables quick and efficient preparation of WGBS libraries from low-input DNA
library preparation methylation epigenetics illumina CpG WGBS Bisulphite single-stranded DNA ssDNAmiRNA libraries from very low input total RNA samples & degraded total RNA.
illumina library preparation epigenetics RNAThe EPIC BeadChip array allows for the interrogation over 935,000 methylation sites quantitatively across the genome at single-nucleotide resolution.
methylation epigenetics illumina dna array infinium CpGOxford Nanopore sequencers perform single-molecule long read sequencing of DNA and RNA
direct RNA epigenetics nanopore long reads ont