A proximity-ligation protocol using a sequence-independent endonuclease, generating data for TAD identification and scaffolding.
TADs illumina de novo chromatin scaffolding library preparation epigeneticsPacBio SMRT sequencing generates reads tens of kilobases in length enabling high quality genome assembly, structural variant analysis, amplicon resequencing, full-length transcript isoform sequencing, full-length 16S rRNA sequencing and amplification free epigenetic characterization.
smrt assembly pacbio methylation amplicon hifi de novo iso seq sv revio